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Hippuric acid

Hippuric acid

CAS: 495-69-2;21251-67-2;66407-11-2;140480-84-8;892119-18-5;892119-19-6

Molecular Formula: C9H9NO3

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Hippuric acid - Names and Identifiers

Name Hippuric acid
Synonyms Hippuric acid
N-Benzoylglycine
2-benzamidoacetic acid
[(phenylcarbonyl)amino]acetate
CAS 495-69-2
21251-67-2
66407-11-2
140480-84-8
892119-18-5
892119-19-6
EINECS 207-806-3
InChI InChI=1/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)/p-1

Hippuric acid - Physico-chemical Properties

Molecular FormulaC9H9NO3
Melting Point188-191℃
Boling Point464.1°C at 760 mmHg
Flash Point234.5°C
Solubility Soluble in hot ethanol, hot water and sodium phosphate aqueous solution, almost insoluble in benzene, carbon disulfide and petroleum ether.
Vapor Presure2.06E-09mmHg at 25°C
AppearanceColorless crystal
Storage Condition2-8℃
SensitiveEasily absorbing moisture
MDLMFCD00002692
Physical and Chemical PropertiesCharacter: colorless crystals.

Melting Point: 188~191 ℃

relative density: 1.371

solubility: insoluble in cold water, soluble in hot water, chloroform, ethanol and ether.
UseFor organic synthesis, medicine and dye intermediates

Hippuric acid - Risk and Safety

Safety DescriptionS24/25 - Avoid contact with skin and eyes.

Hippuric acid - Upstream Downstream Industry

Raw MaterialsBenzoyl chloride
Glycine

Hippuric acid - Reference

Reference
Show more
1. Liu Yi-Wen, Tang Shan-Hu, Li Si-ning, et al. Rapid determination of hippuric acid and benzoic acid in yak dairy products [J]. Food Research and Development, 2019, 40(02):140-147.
2. Sun Jinjie, Jiang Yunsong, Liu Guoying, etc. Identification of two polypeptides in liquor fermented grains and evaluation of their antioxidant and antihypertensive functions [J]. Food and Fermentation Industries, 2019(18).
3. Zhao Yan, Hou Yingying, Tang Guosheng, etc. Inhibitory activity of different extracts of herba epimedii before and after processing on ACE, α-glucosidase and nitrite scavenging activity [J]. Journal of Pharmaceutical Analysis, 2015 (Issue 8):1329-1334.
4. Jiawen Li, Da Liu, Dansheng Liu, et al. Screening and preliminary study on exopolysaccharide-producing strain of lactic acid bacteria [J]. Chinese Journal of microecology, vol. 31, 2019, Issue 9, 1027-1033 pp.
5. Fan Rong, Yi guojuan, Lu Lan, Zeng Ming, Zhou Yangyang, Cheng Qiang. In vitro antibacterial activity of chlorogenic acid and its 13 main metabolites [J]. Chinese herbal medicine, 2020,51(24):6239-6245.
6. [IF = 5.455] Lu Lan et al."Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa."Chin Med-Uk. 2021 Dec;16(1):1-17
7. [IF=5.279] Li-Ming Wang et al."1H NMR and UHPLC/Q-Orbitrap-MS-Based Metabolomics Combined with 16S rRNA Gut Microbiota Analysis Revealed the Potential Regulation Mechanism of Nuciferine in Hyperuricemia Rats."J Agr Food Chem. 2020;68(47):14059-14070
8. [IF=5.275] Sui-Qun Yang et al."Separation and configurational assignment of stereoisomeric phenalenones from the marine mangrove-derived fungus Penicillium herquei MA-370."Bioorg Chem. 2021 Jan;106:104477
9. [IF=5.275] Hong-Lei Li et al."Structurally diverse alkaloids produced by Aspergillus creber EN-602, an endophytic fungus obtained from the marine red alga Rhodomela confervoides."Bioorg Chem. 2021 May;110:104822
10. [IF=4.36] Bao Yang et al."UPLC/Q-TOF-MS/MS-based metabolomics revealed the lipid-lowering effect of Ilicis Rotundae Cortex on high-fat diet induced hyperlipidemia rats."J Ethnopharmacol. 2020 Jun;256:112784
11. [IF=3.935] Zhipeng Wang et al."A rapid and sensitive method for simultaneous determination of eight protein-bound uremic toxins in human serum by UHPLC-MS/MS: application in assessing peritoneal dialysis."J Pharmaceut Biomed. 2020 Jul;186:113312
12. [IF=2.193] Yang Yang et al."Simultaneous Determination of 34 Amino Acids in Tumor Tissues from Colorectal Cancer Patients Based on the Targeted UHPLC-MS/MS Method."J Anal Methods Chem. 2020;2020:4641709
13. [IF=3.739] Liming Wang et al."Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC-MS Analyses."Chem Res Toxicol. 2022;XXXX(XXX):XXX-XXX
14. [IF=3.167] Rongxin Han et al."Physico-chemical properties, antioxidant activity, and ACE inhibitory activity of protein hydrolysates from wild jujube seed."JOURNAL OF FOOD SCIENCE

Hippuric acid - Nature

Open Data Verified Data

colorless crystals. The relative density was 1. 371. The melting point was 188-191 °c. Further heating results in decomposition. Insoluble in cold water, soluble in hot water, chloroform, ethanol and ether.

Last Update：2024-01-02 23:10:35

Hippuric acid - Preparation Method

Open Data Verified Data

glycine is reacted with benzoyl chloride in sodium hydroxide solution to give sodium benzoylaminoacetate, which is then acidified with hydrochloric acid to give a finished product.

Last Update：2022-01-01 10:52:39

Hippuric acid - Introduction

Standard sample for determination of benzoylamino by organic microanalysis.
Last Update：2022-10-16 17:25:28

Hippuric acid - Use

Open Data Verified Data

used in organic synthesis, medicine and dye (such as fluorescent yellow H8GL, disperse fluorescent FFL) intermediate production.

Last Update：2022-01-01 10:52:38

Hippuric acid - Safety

Open Data Verified Data

The bag is packed in plastic bag, 25 kg per bag. Store in a cool, dry place. Protection against heat, sun and moisture.

Last Update：2022-01-01 10:52:39
Hippuric acid
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Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: Hippuric acid Request for quotation
CAS: 495-69-2
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Hippuric acid Request for quotation
CAS: 495-69-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Hippuric acid Request for quotation
CAS: 495-69-2
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Hippuric acid Visit Supplier Webpage Request for quotation
CAS: 495-69-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
SUZHOU YINGKE BIOTECHNOLOGY CO.,LTD
Product Name: Hippuric acid Request for quotation
CAS: 495-69-2
Tel: 13806138270
Email: 2173546588@qq.com
Mobile: 051267215316
QQ: 472241392 Click to send a QQ messageSend QQ message
View History
Hippuric acid
Raw Materials for Hippuric acid
Benzoyl chloride
Glycine
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